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- Oceanwide Expeditions said three passengers died; two onboard and one after disembarkation.
- MV Hondius carried about 150 passengers, sailed from Ushuaia and was off the coast of Cape Verde.
- One infection was laboratory confirmed; five additional suspected cases; officials say link to deaths remains under investigation.
- South Africa health authorities and the National Institute for Communicable Diseases are conducting contact tracing; one patient in Johannesburg intensive care.
- Hantavirus is rodentborne, transmits via inhaling contaminated droppings; only the Andes virus is known to spread person to person.
Three people who were aboard a cruise ship sailing the Atlantic Ocean have died of suspected infections of hantavirus, the World Health Organization said on Sunday, referring to a rare family of viruses carried by rodents.
One case of the infection was confirmed in a laboratory, the organization said in a statement. There are five additional suspected cases, it said.
Of the six people infected, three have died and one person was in intensive care in South Africa, it said.
Foster Mohale, a spokesman for the National Department of Health in South Africa, said passengers of an international cruise ship, MV Hondius, were in South African medical facilities “following serious health complications arising from undiagnosed severe acute respiratory infection.”
The MV Hondius, which was carrying about 150 passengers from various countries, left Ushuaia in Argentina about three weeks ago for the Canary Islands, stopping in mainland Antarctica, the Falkland Islands, South Georgia, Nightingale Island, Tristan, St. Helena, Ascension and Cape Verde, Mr. Mohale said.
In a statement on Sunday, the operator of the ship, Oceanwide Expeditions, said it was closely monitoring the situation “and is deploying all available resources to ensure appropriate medical care and support for passengers and crew.”
The ship, the operator said, is off the coast of Cape Verde.
“During this voyage, three passengers have passed away,” the statement said. “Two of these deaths occurred on board the vessel, and one occurred after disembarkation. In addition, one passenger is currently being treated in intensive care in Johannesburg, and two individuals on board require urgent medical care.”
Oceanwide said the cause of the infections remained under investigation.
“At this stage, it has not been established whether hantavirus is linked to the three deaths connected to this voyage,” it said. “Hantavirus has not been confirmed in the two symptomatic individuals currently on board.”
It added that health authorities have been aboard to assess the conditions of the two symptomatic people and that a decision about transferring them to seek medical care in Cape Verde was pending.
One of the patients, a 70-year-old male passenger, became ill and was experiencing a fever, headache, abdominal pain and diarrhea, Mr. Mohale said.
The passenger died on arrival in St. Helena Island, he said, and his remains were awaiting repatriation to Netherlands.
The victim’s 69-year-old wife also became ill on board and collapsed at the O.R. Tambo International Airport in South Africa while trying to fly home to the Netherlands. She was taken to a health facility, where she died.
Another patient was a British national who became ill while the ship was traveling from St. Helena to Ascension Island and was transferred from a hospital in Ascension to a private South African health facility in Sandton.
His laboratory test results came back positive for hantavirus, Mr. Mohale said.
The department is working with the National Institute for Communicable Diseases and Gauteng Health authorities to conduct contact tracing, Mr. Mohale said.
“There is no need for the public to panic because only two patients from the cruise ship have been within our borders,” Mr. Mohale said, adding that the “World Health Organization is coordinating a multicountry response with all affected islands and countries to contain further spread of the disease.”
Hantavirus refers to a family of viruses that are carried by rodents. It is often transmitted to humans by inhaling particles of dried deer mouse droppings or urine. The only hantavirus documented to have spread person-to-person is the Andes virus, found in South America, according to the federal Centers for Disease Control and Prevention.
Experts said the virus was not typically associated with cruise ships, which can be incubators for illnesses like the coronavirus or norovirus, which are known to spread rapidly among people.
“I don’t know of any other cases reported on a cruise ship before,” Emily Abdoler, a doctor and assistant professor of medicine at the University of Michigan Medical School, said of the hantavirus.
She and another expert said possible origins of the virus included rodent droppings on the ship itself, or at a location where it had docked. Given the ship had been in South America, it was also possible that the virus had spread between people, Dr. Abdoler said.
“This is not a common infection, but it’s even less common to have the human spread raised as a possibility,” she added. “Six people sick on a cruise ship — I’ve never heard of that from this kind of infection.”
At first, hantavirus causes flulike symptoms, including fever, chills, body aches and headaches. But as the disease progresses, respiratory symptoms develop and patients can experience shortness of breath and then lung or heart failure.
The disease made headlines last year after Betsy Arakawa, the wife of the actor Gene Hackman, died from the effects of the virus.
The Centers for Disease Control and Prevention reported 890 cases of hantavirus as of the end of 2023 since surveillance began in 1993.
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